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KMID : 0616120230540040219
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Korean Journal of Pharmacognosy
2023 Volume.54 No. 4 p.219 ~ p.224
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Evaluation of Camptothin B Contents by Season and Region Isolated from Cornus alba
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Son Se-Yeon
Oh Jae-Yoon
Seonu Seo-Yeon
Jin Si-Yeon
Choi Jin-Hyeok
Kim Kyung-Mi
Lee Min-Won
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Abstract
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Cornus alba (CA) has been used as a hemostatic and diuretic treatments in Korea. Previously, it was reported that CA and its isolated component, camptothin B (1), have excellent pharmacological activities including antioxidant, anti-inflammatory and inhibition of 5α-reductase on Benign Prostatic Hyperplasia. In this study, quantitative analysis was performed using high-performance liquid chromatography (HPLC) to evaluate the seasonal and regional contents of 1 isolated from CA. The analysis method of 1 was verified by reviewing validation guideline. And the content by season and region of 1 was in the range of 3.12~6.27% in ethanolic extract of CA.
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KEYWORD
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Content, Cornus alba, Ellagitannins, Camptothin B
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